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Antibodies

TTR Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22144-20UL
60 ul
£183.00
E-AB-22144-60UL
120 ul
£272.00
E-AB-22144-120UL
200 ul
£420.00
E-AB-22144-200UL
About this Product
SKU:
E-AB-22144
Additional Names:
ATTR;Amyloid polyneuropathy;Amyloidosis I;CTS;CTS1;Carpal tunnel syndrome 1;Dysprealbuminemic euthyroidal hyperthyroxinemia;Dystransthyretinemic hyperthyroxinemia;Epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin;Prealbumin amyloidosis type I
Application:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
2A4
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Host:
Mouse
Immunogen:
Recombinant Protein of TTR
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody