ACTN1 Monoclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-22127-20UL
60 ul
£183.00
E-AB-22127-60UL
120 ul
£272.00
E-AB-22127-120UL
200 ul
£420.00
E-AB-22127-200UL
About this Product
- SKU:
- E-AB-22127
- Additional Names:
- ACTN 1,ACTN1,Actinin alpha 1,Actn1,Alpha Actinin 1,Alpha actinin cytoskeletal isoform,Alpha-actinin cytoskeletal isoform,Alpha-actinin-1,BDPLT15,F,F actin cross linking protein,F-actin cross-linking protein,FLJ40884,actinin,actinin 1 smooth muscle,alpha 1
- Application:
- IHC-Paraffin, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 1D4
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Host:
- Mouse
- Immunogen:
- Recombinant Protein of a-actinin of ACTN1
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-actn1_monoclonal_antibody-e_ab_22127
