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Antibodies

PPARD Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22126-20UL
60 ul
£183.00
E-AB-22126-60UL
120 ul
£272.00
E-AB-22126-120UL
200 ul
£420.00
E-AB-22126-200UL
About this Product
SKU:
E-AB-22126
Additional Names:
FAAR,MGC3931,NR1C2,NUC1,NUCI,NUCII,Nuclear hormone receptor 1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferative activated receptor delta,Peroxisome proliferator-activated rec,Peroxisome proliferator-activated receptor beta (PPAR-beta)
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
5F4
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway.
Host:
Mouse
Immunogen:
Recombinant Protein of PPAR Delta of PPAR Delta
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody