Active CASP3 Monoclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-22115-20UL
60 ul
£183.00
E-AB-22115-60UL
120 ul
£272.00
E-AB-22115-120UL
200 ul
£420.00
E-AB-22115-200UL
About this Product
- SKU:
- E-AB-22115
- Additional Names:
- A830040C14Rik;Apopain;CASP-3;CASP3;CC3;CPP-32;CPP32;CPP32B;Casp3a;Caspase 3;Caspase-3 subunit p12;Cysteine p;apoptosis-related cysteine peptidase;apoptosis-related cysteine protease;apoptosis-related cysteine protease a
- Application:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5A2
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- Host:
- Mouse
- Immunogen:
- Recombinant Protein
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-active_casp3_monoclonal_antibody-e_ab_22115
