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Antibodies

MICU1 Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22114-20UL
60 ul
£183.00
E-AB-22114-60UL
120 ul
£272.00
E-AB-22114-120UL
200 ul
£420.00
E-AB-22114-200UL
About this Product
SKU:
E-AB-22114
Additional Names:
Allergen Hom s 4,Atopy-related autoantigen CALC,CALC,Calcium uptake protein 1,Calcium-binding atopy-relate,ara CALC,atopy related autoantigen,atopy related autoantigen CALC,calcium binding atopy related autoantigen 1,calcium uptake protein 1,mitochondrial
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
4E7
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
Host:
Mouse
Immunogen:
Recombinant Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody