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Antibodies

Histone H2B Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22086-20UL
60 ul
£183.00
E-AB-22086-60UL
120 ul
£272.00
E-AB-22086-120UL
200 ul
£420.00
E-AB-22086-200UL
About this Product
SKU:
E-AB-22086
Additional Names:
(testis specific),H2B,H2B histone family,H2B histone family member U,H2B histone family member U testis specific,H2B testis,H2B1A,H2BFU,H2BT,H2ba,HIST1H2BA,Histone 1,Histone H2B,Histone H2B testi,Histone cluster 1 H2ba,bA317E16.3,member U,testis
Application:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
3C3
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
Host:
Mouse
Immunogen:
Synthetic Peptide
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody