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Antibodies

XRCC4 Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22044-20UL
60 ul
£183.00
E-AB-22044-60UL
120 ul
£272.00
E-AB-22044-120UL
200 ul
£420.00
E-AB-22044-200UL
About this Product
SKU:
E-AB-22044
Additional Names:
DNA double strand break repair and V(D)J recombination protein XRCC4,DNA repair protein XRCC4,SSMED,X ray repair complementing defective repair in Chinese hamster cells 4,X ray repair cross complementing 4,X ray repair cross complementing protein 4,X-ray
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
8K2
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Host:
Mouse
Immunogen:
Synthetic Peptide
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody