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Antibodies

KIF7 Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22026-20UL
60 ul
£183.00
E-AB-22026-60UL
120 ul
£272.00
E-AB-22026-120UL
200 ul
£420.00
E-AB-22026-200UL
About this Product
SKU:
E-AB-22026
Additional Names:
EQYK340,KIF7,Kinesin-like protein kif7,UNQ340,kif7,kinesin family member 7,kinesin like protein KIF7
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
3I4
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
Host:
Mouse
Immunogen:
Synthetic Peptide
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody