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Antibodies

AMACR Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22010-20UL
60 ul
£183.00
E-AB-22010-60UL
120 ul
£272.00
E-AB-22010-120UL
200 ul
£420.00
E-AB-22010-200UL
About this Product
SKU:
E-AB-22010
Additional Names:
2 methylacyl CoA racemase,2-methylacyl-CoA racemase,AMACR,AMACRD,Alpha methylacyl CoA racemase,Alpha-methylacyl-CoA racemase,Amacr,CBAS4,EC 5.1.99.4,Macr1,RACE,RM
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
1F1
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Host:
Mouse
Immunogen:
Synthetic Peptide
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody