Phospho-ATM (Ser1981) Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-21540-20UL
60 ul
£183.00
E-AB-21540-60UL
120 ul
£272.00
E-AB-21540-120UL
200 ul
£420.00
E-AB-21540-200UL
About this Product
- SKU:
- E-AB-21540
- Additional Names:
- A-T mutated,A-T mutated homolog,AT mutated,AT1,ATA,ATC,ATD,ATDC,ATE,ATM,ATM serine/threonine kinase,Ataxia telangiectasia mutated,Ataxia telangiectasia mutated gene,Ataxia telangiectasia mutated homolog,Ataxia telangiectasia mutated homolog (human),DK
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Atm around the phosphorylation site of Ser1981
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-phospho_atm_(ser1981)_polyclonal_antibody-e_ab_21540
