Phospho-PAK1 (Thr212) Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-21179-20UL
60 ul
£183.00
E-AB-21179-60UL
120 ul
£272.00
E-AB-21179-120UL
200 ul
£420.00
E-AB-21179-200UL
About this Product
- SKU:
- E-AB-21179
- Additional Names:
- ADRB2,Alpha PAK,Alpha-PAK,MGC130000,MGC130001,p21 activated kinase 1,p21 protein (Cdc42/Rac) activated kinase 1,p21-activated kinase 1,p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related),p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog,p65 PAK,yeast)
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human PAKA Alpha around the phosphorylation site of Thr212
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-phospho_pak1_(thr212)_polyclonal_antibody-e_ab_21179
