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Antibodies

Acetyl-P53 (Lys381) Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-20287-20UL
60 ul
£183.00
E-AB-20287-60UL
120 ul
£272.00
E-AB-20287-120UL
200 ul
£420.00
E-AB-20287-200UL
About this Product
SKU:
E-AB-20287
Additional Names:
Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;P53;Phosphoprotein p53;TRP53;Tp53;Transformation related protein 53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53;p53;p53 tumor suppressor
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human p53 around the acetylation site of K381
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody