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Antibodies

RGR Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19982-20UL
60 ul
£183.00
E-AB-19982-60UL
120 ul
£272.00
E-AB-19982-120UL
200 ul
£420.00
E-AB-19982-200UL
About this Product
SKU:
E-AB-19982
Additional Names:
RGR-opsin,RP44,RPE retinal G protein coupled receptor,Ral GDS related protein,Retinal G protein coupled receptor,hRGR
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
Synthetic peptide of human RGR
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody