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Antibodies

GFI1B Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19907-20UL
60 ul
£183.00
E-AB-19907-60UL
120 ul
£272.00
E-AB-19907-120UL
200 ul
£420.00
E-AB-19907-200UL
About this Product
SKU:
E-AB-19907
Additional Names:
GFI 1B,GFI1B,GFI1B protein,Growth factor independent 1B protein,Growth factor independent 1B transcription repressor,Growth factor independent protein 1B,OTTHUMP00000022443,OTTHUMP00000022444,OTTHUMP000000235527,Potenti,Potential regulator of CDKN1A,gfi1b
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.72 mg/ml
Extra Details:
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.GFI1B (Growth Factor Independent 1B Transcriptional Repressor) is a Protein Coding gene. Diseases associated with GFI1B include Bleeding Disorder, Platelet-Type, 17 and Gray Platelet Syndrome. Among its related pathways are NF-kappaB Signaling. GO annotations related to this gene include RNA polymerase II transcription factor binding. An important paralog of this gene is GFI1.
Host:
Rabbit
Immunogen:
Synthetic peptide of human GFI1B
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody