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Antibodies

ACOD1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19833-20UL
60 ul
£183.00
E-AB-19833-60UL
120 ul
£272.00
E-AB-19833-120UL
200 ul
£420.00
E-AB-19833-200UL
About this Product
SKU:
E-AB-19833
Additional Names:
ACOD1,Aconitate decarboxylase,Aconitate decarboxylase 1,CAD,Cis aconitate decarboxylase,IRG1,Immune responsive gene 1 protein homolog,Immune-responsive gene 1 protein homolog,Immunoresponsive 1 homolog (mouse),Irg1,OC116,OPTB1,TCTIRC7
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.32 mg/ml
Extra Details:
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Host:
Rabbit
Immunogen:
Synthetic peptide of human ACOD1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody