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Antibodies

KLF1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19799-20UL
60 ul
£183.00
E-AB-19799-60UL
120 ul
£272.00
E-AB-19799-120UL
200 ul
£420.00
E-AB-19799-200UL
About this Product
SKU:
E-AB-19799
Additional Names:
CDAN4,EKLF,EKLF PEN,Erythroid Kruppel like factor,Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor),Erythroid krueppel-like transcription factor,Erythroid specific transcription factor EKLF,HBFQTL6,Human erythroid-specif
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.96 mg/ml
Extra Details:
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
Host:
Rabbit
Immunogen:
Synthetic peptide of human KLF1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody