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Antibodies

HIST1H2BA Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19784-20UL
60 ul
£183.00
E-AB-19784-60UL
120 ul
£272.00
E-AB-19784-120UL
200 ul
£420.00
E-AB-19784-200UL
About this Product
SKU:
E-AB-19784
Additional Names:
(testis specific),H2B,H2B histone family,H2B histone family member U,H2B histone family member U testis specific,H2B testis,H2B1A,H2BFU,H2BT,H2ba,HIST1H2BA,Histone 1,Histone H2B,Histone H2B testi,Histone cluster 1 H2ba,bA317E16.3,member U,testis
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.98 mg/ml
Extra Details:
The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
Host:
Rabbit
Immunogen:
Synthetic peptide of human HIST1H2BA
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody