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Antibodies

CDH12 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19682-20UL
60 ul
£183.00
E-AB-19682-60UL
120 ul
£272.00
E-AB-19682-120UL
200 ul
£420.00
E-AB-19682-200UL
About this Product
SKU:
E-AB-19682
Additional Names:
BR-cadherin,Br cadherin,Brain cadherin,CAD12_HUMAN,CDH12,CDHB,Cadherin 12,Cadherin 12 precursor,Cadherin 12 type 2,Cadherin 12 type 2 (N cadherin 2),Cadherin neural type 2,Cadherin-12,FLJ34857,N cadherin 2,N-cadherin 2,Neural ty,cadherin 12 (N cadherin 2)
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.74 mg/ml
Extra Details:
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CDH12
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody