CAD Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19652-20UL
60 ul
£183.00
E-AB-19652-60UL
120 ul
£272.00
E-AB-19652-120UL
200 ul
£420.00
E-AB-19652-200UL
About this Product
- SKU:
- E-AB-19652
- Additional Names:
- Aspartate carbamoyltransferase,Aspartate transcarbamylase,CAD protein,CAD trifunctional protein,CPSase ATCase DHOase,Carbamoyl phosphate synthetase 2,Carbamoyl-phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase,Dihydroorotase,Glutamine d
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CAD
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cad_polyclonal_antibody-e_ab_19652
