ATRX Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19609-20UL
60 ul
£183.00
E-AB-19609-60UL
120 ul
£272.00
E-AB-19609-120UL
200 ul
£420.00
E-AB-19609-200UL
About this Product
- SKU:
- E-AB-19609
- Additional Names:
- X linked,ATP dependent helicase ATRX,ATP-dependent helicase ATRX,ATR2,ATRX,Alpha thalassemia/mental retardation syndrome X linked homolog,Atrx,DNA dependent ATPase and helicase,Helicase 2,MGC2094,MRXHF1,RAD54,RAD54L,SFM1,SHS,Transcriptional regulator ATR
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins.This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis.Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome.These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes.Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ATRX
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-atrx_polyclonal_antibody-e_ab_19609
