HUWE1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19540-20UL
60 ul
£183.00
E-AB-19540-60UL
120 ul
£272.00
E-AB-19540-120UL
200 ul
£420.00
E-AB-19540-200UL
About this Product
- SKU:
- E-AB-19540
- Additional Names:
- ARF BP1,ARF binding protein 1,ARF-BP1,ARF-binding protein 1,BJ-HCC-24 tumor antigen,E3 ubiquitin protein ligase HUWE1,E3 ubiquitin-protein ligase HUWE1,HECT,HECT UBA and WWE domain containing protein 1,HECT domain protein LASU1,HectH9,Homologous to E6AP c
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HUWE1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-huwe1_polyclonal_antibody-e_ab_19540
