DPPA4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19445-20UL
60 ul
£183.00
E-AB-19445-60UL
120 ul
£272.00
E-AB-19445-120UL
200 ul
£420.00
E-AB-19445-200UL
About this Product
- SKU:
- E-AB-19445
- Additional Names:
- 2410091M23Rik,DPPA4,Developmental pluripotency associated 4,Developmental pluripotency associated protein 4,Developmental pluripotency-associated protein 4,Dppa 4,FLJ10713
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.56 mg/ml
- Extra Details:
- This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human DPPA4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dppa4_polyclonal_antibody-e_ab_19445
