HIPK3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19326-20UL
60 ul
£183.00
E-AB-19326-60UL
120 ul
£272.00
E-AB-19326-120UL
200 ul
£420.00
E-AB-19326-200UL
About this Product
- SKU:
- E-AB-19326
- Additional Names:
- ANPK,Androgen receptor interacting nuclear protein kinase,Androgen receptor-interacting nuclear protein kinase,DYRK6,FIST,FIST3,Fas interacting serine/threonine protein kinase,Fas-interacting serine/threonine-protein kinase,HIPK3,Hipk3,homeodomain interac
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HIPK3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hipk3_polyclonal_antibody-e_ab_19326
