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Antibodies

SPACA1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19214-20UL
60 ul
£183.00
E-AB-19214-60UL
120 ul
£272.00
E-AB-19214-120UL
200 ul
£420.00
E-AB-19214-200UL
About this Product
SKU:
E-AB-19214
Additional Names:
SACA1,SAMP32,SPACA1,Sperm acrosomal membrane-associated protein 32,Sperm acrosome membrane-associated protein 1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.84 mg/ml
Extra Details:
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Host:
Rabbit
Immunogen:
Fusion protein of human SPACA1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody