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Antibodies

KCNIP3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-19200-20UL
60 ul
£183.00
E-AB-19200-60UL
120 ul
£272.00
E-AB-19200-120UL
200 ul
£420.00
E-AB-19200-200UL
About this Product
SKU:
E-AB-19200
Additional Names:
4933407H12Rik;A type potassium channel modulatory protein 3;A-type potassium channel modulatory protein 3;AI413860;CSEN;Calsenilin;DRE antagonist modulator;DRE-antagonist modulator;DREAM;EF hand transcription factor;KCHIP 3;KCNIP 3;KChIP3;Kcnip3;Kv c
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1.62 mg/ml
Extra Details:
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.
Host:
Rabbit
Immunogen:
Fusion protein of human KCNIP3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody