RIC8A Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19028-20UL
60 ul
£183.00
E-AB-19028-60UL
120 ul
£272.00
E-AB-19028-120UL
200 ul
£420.00
E-AB-19028-200UL
About this Product
- SKU:
- E-AB-19028
- Additional Names:
- MGC104517,MGC131931,MGC148073,MGC148074,Protein Ric-8A,RIC8,RIC8A,Synembryn-A,resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.96 mg/ml
- Extra Details:
- Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human RIC8A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ric8a_polyclonal_antibody-e_ab_19028
