FDPS Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19027-20UL
60 ul
£183.00
E-AB-19027-60UL
120 ul
£272.00
E-AB-19027-120UL
200 ul
£420.00
E-AB-19027-200UL
About this Product
- SKU:
- E-AB-19027
- Additional Names:
- Dimethylallyltranstransferase,FPP synthase,FPP synthetase,FPPS,FPPS_HUMAN,FPS,Farnesyl diphosphate synthase,Farnesyl diphosphate synthetase,Farnesyl pyrophosphate synthase,Farnesyl pyrophosphate synthetase,Fdps,Geranyltranstransferase
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.02 mg/ml
- Extra Details:
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human FDPS
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fdps_polyclonal_antibody-e_ab_19027
