SF3B3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19022-20UL
60 ul
£183.00
E-AB-19022-60UL
120 ul
£272.00
E-AB-19022-120UL
200 ul
£420.00
E-AB-19022-200UL
About this Product
- SKU:
- E-AB-19022
- Additional Names:
- KIAA0017;Pre mRNA splicing factor SF3b 130 kDa subunit;Pre-mRNA-splicing factor SF3b 130 kDa subunit;RSE1;SAP 130;SAP130;SF3B3;SF3B3_HUMAN;SF3b130;Spl;Spliceosome associated protein 130;Spliceosome-associated protein 130;Splicing factor 3b subunit 3 130kD
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.2 mg/ml
- Extra Details:
- This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human SF3B3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-sf3b3_polyclonal_antibody-e_ab_19022
