ELF3 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-19002-20UL
60 ul
£183.00
E-AB-19002-60UL
120 ul
£272.00
E-AB-19002-120UL
200 ul
£420.00
E-AB-19002-200UL
About this Product
- SKU:
- E-AB-19002
- Additional Names:
- E74 like factor 3,E74 like factor 3 ETS domain transcription factor serine box epithelial specific,E74 like factor 3 ets domain transcription factor,E74 like factor 3 ets domain transcription factor epithelial specific,E74-like factor 3,ELF3,Elf3,Epitheli
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.68 mg/ml
- Extra Details:
- Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human ELF3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-elf3_polyclonal_antibody-e_ab_19002
