DUSP7 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18976-20UL
60 ul
£183.00
E-AB-18976-60UL
120 ul
£272.00
E-AB-18976-120UL
200 ul
£420.00
E-AB-18976-200UL
About this Product
- SKU:
- E-AB-18976
- Additional Names:
- DUS7,Dual specificity phosphatase 7,Dual specificity protein phosphatase 7,Dual specificity protein phosphatase PYST2,Dusp7,JSP1,Jnk Stimulatory Phosphatase 1,MAP kinase phosphatase X,MKPX,PYST2
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.72 mg/ml
- Extra Details:
- Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human DUSP7
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dusp7_polyclonal_antibody-e_ab_18976
