NIPBL Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18915-20UL
60 ul
£183.00
E-AB-18915-60UL
120 ul
£272.00
E-AB-18915-120UL
200 ul
£420.00
E-AB-18915-200UL
About this Product
- SKU:
- E-AB-18915
- Additional Names:
- CDLS,Colon tumor susceptibility 2,DKFZp434L1319,Delangin,FLJ11203,FLJ12597,FLJ13354,FLJ13648,FLJ44854,IDN 3,IDN 3 protein,IDN 3 protein isoform A,IDN 3 protein isoform B,IDN 3B,IDN3 B,IDN3 protein,IDN3 protein isoform A,IDN3 protein isoform B,IDN3B,Mis 4
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human NIPBL
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-nipbl_polyclonal_antibody-e_ab_18915
