ENSA Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18885-20UL
60 ul
£183.00
E-AB-18885-60UL
120 ul
£272.00
E-AB-18885-120UL
200 ul
£420.00
E-AB-18885-200UL
About this Product
- SKU:
- E-AB-18885
- Additional Names:
- ARPP 19e ,Alpha endosulfine ,Endosulfine alpha
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.72 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human ENSA
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ensa_polyclonal_antibody-e_ab_18885
