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Antibodies

GTF2A2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18882-20UL
60 ul
£183.00
E-AB-18882-60UL
120 ul
£272.00
E-AB-18882-120UL
200 ul
£420.00
E-AB-18882-200UL
About this Product
SKU:
E-AB-18882
Additional Names:
12kDa, 2, 2 (12kD subunit),General transcription factor IIA,General transcription factor IIA subunit 2,HsT18745,T2AG,TF2A2,TFI,TFIIA,TFIIA 12,TFIIA gamma ,TFIIA p12 subunit,TFIIA-12,gtf2a2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.54 mg/ml
Extra Details:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
Host:
Rabbit
Immunogen:
Fusion protein of human GTF2A2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody