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Antibodies

ISCU Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18785-20UL
60 ul
£183.00
E-AB-18785-60UL
120 ul
£272.00
E-AB-18785-120UL
200 ul
£420.00
E-AB-18785-200UL
About this Product
SKU:
E-AB-18785
Additional Names:
2310020H20Rik,HML,ISCU,Iron sulfur cluster assembly enzyme ISCU mitochondrial,Iron sulfur cluster scaffold homolog,Iron sulfur cluster scaffold homolog (E. coli),Iron-sulfur cluster assembly enzyme ISCU,IscU iron sulfur cluster scaffold homolog,Iscu,hnifU
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.96 mg/ml
Extra Details:
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Host:
Rabbit
Immunogen:
Fusion protein of human ISCU
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody