RNF111 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18773-20UL
60 ul
£183.00
E-AB-18773-60UL
120 ul
£272.00
E-AB-18773-120UL
200 ul
£420.00
E-AB-18773-200UL
About this Product
- SKU:
- E-AB-18773
- Additional Names:
- ARK,Arkadia,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,E3 ubiquitin protein ligase Arkadia,E3 ubiquitin-protein ligase Arkadia,FLJ38008,RING finger protein 111,RN111,RNF 111,RNF111
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.84 mg/ml
- Extra Details:
- The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase.This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription.As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human RNF111
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rnf111_polyclonal_antibody-e_ab_18773
