C9orf116 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18760-20UL
60 ul
£183.00
E-AB-18760-60UL
120 ul
£272.00
E-AB-18760-120UL
200 ul
£420.00
E-AB-18760-200UL
About this Product
- SKU:
- E-AB-18760
- Additional Names:
- C9orf116,CI116,Pierce 1,UPF0691 protein C9orf116
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.96 mg/ml
- Extra Details:
- C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human C9orf116
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-c9orf116_polyclonal_antibody-e_ab_18760
