NARF Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18713-20UL
60 ul
£183.00
E-AB-18713-60UL
120 ul
£272.00
E-AB-18713-120UL
200 ul
£420.00
E-AB-18713-200UL
About this Product
- SKU:
- E-AB-18713
- Additional Names:
- DKFZp434G0420,FLJ10067,GC17P078009,IOP2,Iron only hydrogenase like protein 2,Nuclear prelamin A recognition factor,Prenyl dependent prelamin A binding protein
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.56 mg/ml
- Extra Details:
- Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends.Prenylation was initially believed to be important only for membrane attachment.However, another role for prenylation appears to be its importance in protein-protein interactions.The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins.Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif.This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A.The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain.It may be a component of a prelamin A endoprotease complex.The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina.It shares limited sequence similarity with iron-only bacterial hydrogenases.Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human NARF
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-narf_polyclonal_antibody-e_ab_18713
