DENND1B Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18656-20UL
60 ul
£183.00
E-AB-18656-60UL
120 ul
£272.00
E-AB-18656-120UL
200 ul
£420.00
E-AB-18656-200UL
About this Product
- SKU:
- E-AB-18656
- Additional Names:
- C1ORF18,C1orf218 ,Chromosome 1 open reading frame 218,Connecdenn 2,DEN1B,DENN MADD domain containing 1B,DENN domain containing protein 1B,DENN domain-containing protein 1B,DENND1B,DKFZp547O0715,FAM31B ,FLJ20054,Family with sequence similarity 31 member B
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.54 mg/ml
- Extra Details:
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human DENND1B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dennd1b_polyclonal_antibody-e_ab_18656
