COMT Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18624-20UL
60 ul
£183.00
E-AB-18624-60UL
120 ul
£272.00
E-AB-18624-120UL
200 ul
£420.00
E-AB-18624-200UL
About this Product
- SKU:
- E-AB-18624
- Additional Names:
- COMT,Catechol O methyltransferase,Catechol O-methyltransferase,EC 2.1.1.6
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.02 mg/ml
- Extra Details:
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human COMT
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-comt_polyclonal_antibody-e_ab_18624
