CHRD Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18617-20UL
60 ul
£183.00
E-AB-18617-60UL
120 ul
£272.00
E-AB-18617-120UL
200 ul
£420.00
E-AB-18617-200UL
About this Product
- SKU:
- E-AB-18617
- Additional Names:
- CHRD,Chordin,MGC133038,SOG,Shortgastrulation protein,chrd
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and TGF-beta signaling pathway (KEGG). GO annotations related to this gene include heparin binding and syndecan binding. An important paralog of this gene is CHRDL2.This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CHRD
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-chrd_polyclonal_antibody-e_ab_18617
