CEP57 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18608-20UL
60 ul
£183.00
E-AB-18608-60UL
120 ul
£272.00
E-AB-18608-120UL
200 ul
£420.00
E-AB-18608-200UL
About this Product
- SKU:
- E-AB-18608
- Additional Names:
- CEP57,Centrosomal protein 57kDa,Centrosomal protein of 57 kDa,Cep57,Cep57 protein,FGF2 interacting protein,FGF2-interacting protein,KIAA0092,MVA2,PIG8,Proliferation inducing protein 8,TSP57,Testis specific protein 57,Testis-specific protein 57,Translokin
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.42 mg/ml
- Extra Details:
- This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Host:
- Rabbit
- Immunogen:
- Full length fusion protein
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cep57_polyclonal_antibody-e_ab_18608
