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Antibodies

FAM110B Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18575-20UL
60 ul
£183.00
E-AB-18575-60UL
120 ul
£272.00
E-AB-18575-120UL
200 ul
£420.00
E-AB-18575-200UL
About this Product
SKU:
E-AB-18575
Additional Names:
Chromosome 8 open reading frame 72;F110B;Fam110b;Family with sequence similarity 110 member B;Protein FAM110B
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
FAM110B (Familiarity with sequence similarity 110, member B) is a 370 amino acid protein, which contains several motifs that are conserved among FAM110 family members and a proline-rich region through which it probably binds proteins. Localized to the nucleus where they associate with centrosomes, FAM110A, FAM110B and FAM110C accumulate at the spindle poles during mitosis. Expression of FAM110B and FAM110C impairs cell cycle progression through G1 phase. FAM110B is expressed in testis, thyroid and spleen and is found at lower levels in ovary, adrenal gland, stomach, trachea, intestine, lymph node, spinal cord and prostate. The gene encoding FAM110B maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. May be involved in tumor progression.
Host:
Rabbit
Immunogen:
Fusion protein of human FAM110B
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody