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Antibodies

BAIAP2L1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18531-20UL
60 ul
£183.00
E-AB-18531-60UL
120 ul
£272.00
E-AB-18531-120UL
200 ul
£420.00
E-AB-18531-200UL
About this Product
SKU:
E-AB-18531
Additional Names:
BAI1 associated protein 2 like 1,BAI1 associated protein 2 like protein 1,BAI1-associated protein 2-like protein 1,BI2L1,Baiap2l1,Brain specific angiogenesis inhibitor 1 associated protein 2 like protein 1,Brain-specific angiogenesis inhibitor 1-associate
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
Host:
Rabbit
Immunogen:
Fusion protein of human BAIAP2L1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody