UNC13B Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18509-20UL
60 ul
£183.00
E-AB-18509-60UL
120 ul
£272.00
E-AB-18509-120UL
200 ul
£420.00
E-AB-18509-200UL
About this Product
- SKU:
- E-AB-18509
- Additional Names:
- MGC133279,MGC133280,Munc13-2,Protein unc-13 homolog B,UN13B,UNC13,Unc13b,Unc13h2,hmunc13,munc13,unc-13 homolog B (C. elegans)
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human UNC13B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-unc13b_polyclonal_antibody-e_ab_18509
