PRNP Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18439-20UL
60 ul
£183.00
E-AB-18439-60UL
120 ul
£272.00
E-AB-18439-120UL
200 ul
£420.00
E-AB-18439-200UL
About this Product
- SKU:
- E-AB-18439
- Additional Names:
- major prion protein;ASCR;AltPrP;Alternative prion protein;CD230;CD230 antigen;CJD;GSS;KURU;Major prion protein;PRIO;PRIP;PRNP;PrP;PrP27 30 ;PrP27-30;PrP33-35C;PrPC;PrPSc;Prion protein;Prion related protein;Sinc;p27 30
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human PRNP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-prnp_polyclonal_antibody-e_ab_18439
