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Antibodies

GRAP Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18391-20UL
60 ul
£183.00
E-AB-18391-60UL
120 ul
£272.00
E-AB-18391-120UL
200 ul
£420.00
E-AB-18391-200UL
About this Product
SKU:
E-AB-18391
Additional Names:
GRAP,GRB2 related adaptor protein,GRB2-related adapter protein,Grap,Growth factor receptor bound protein 2 related adaptor protein,MGC64880,OTTHUMP00000065766
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Host:
Rabbit
Immunogen:
Full length fusion protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody