ATF6B Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18330-20UL
60 ul
£183.00
E-AB-18330-60UL
120 ul
£272.00
E-AB-18330-120UL
200 ul
£420.00
E-AB-18330-200UL
About this Product
- SKU:
- E-AB-18330
- Additional Names:
- ATF6-beta,ATF6B,Activating transcription factor 6 beta,CREBL1,Cyclic AMP-dependent transcription factor ATF-6 beta,G13,Protein G13,cAMP response element-binding protein-related protein,cAMP-dependent transcription factor ATF-6 beta
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human ATF6B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-atf6b_polyclonal_antibody-e_ab_18330
