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Antibodies

TBP Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18293-20UL
60 ul
£183.00
E-AB-18293-60UL
120 ul
£272.00
E-AB-18293-120UL
200 ul
£420.00
E-AB-18293-200UL
About this Product
SKU:
E-AB-18293
Additional Names:
GTF2D,GTF2D1,HDL4,SCA17,TATA binding factor,TATA box binding protein,TATA box factor,TATA sequence binding protein,TATA sequence-binding protein,TATA-binding factor,TATA-box factor,TATA-box-binding protein,TBP,TFIID,Transcription initiation factor TFI
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP,along with a variety of TBP-associated factors,make up the TFIID,a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner,it helps position RNA polymerase II over the transcription start site of the gene. However,it is estimated that only 10-20% of human promoters have TATA boxes. Therefore,TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa).
Host:
Rabbit
Immunogen:
Full length fusion protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody