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Antibodies

ABI2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-18253-20UL
60 ul
£183.00
E-AB-18253-60UL
120 ul
£272.00
E-AB-18253-120UL
200 ul
£420.00
E-AB-18253-200UL
About this Product
SKU:
E-AB-18253
Additional Names:
ABI 2,ABI2,ABI2B,AIP 1,Abelson interactor 2,Abi-2,Abl binding protein 3,Abl interacting protein 1 (SH3 containing protein),Abl interactor 2,Abl interactor protein 2b,Abl-binding protein 3,AblBP3,Arg binding protein 1,Arg protein tyrosine kinase bindi
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
Host:
Rabbit
Immunogen:
Fusion protein of human ABI2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody