PCNA Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-18205-20UL
60 ul
£183.00
E-AB-18205-60UL
120 ul
£272.00
E-AB-18205-120UL
200 ul
£420.00
E-AB-18205-200UL
About this Product
- SKU:
- E-AB-18205
- Additional Names:
- ATLD2,Cyclin,DNA polymerase delta auxiliary protein,HGCN8729,MGC8367,Mutagen-sensitive 209 protein,OTTHUMP00000030189,OTTHUMP00000030190,PCNA,PCNAR,Pcna/cyclin,Polymerase delta accessory protein,Proliferating cell nu,cb16,etID36690.10,fa28e03,fb36g03
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- Proliferating Cell Nuclear Antigen,commonly known as PCNA,is a protein that acts as a processivity factor for DNA polymerase D Delta in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase,but not apurinic-apyrimidinic (AP) endonuclease,APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution, the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human PCNA
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-pcna_polyclonal_antibody-e_ab_18205
